Disease: Hyperlipidemia
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ZPR1 O75312 ZPR1 zinc finger 8.9E-09 0.674 0.462
VLDLR P98155 very low density lipoprotein receptor 2.0E-11 0.558 0.692
TRH P20396 thyrotropin releasing hormone 8.9E-04 0.519 0.846
ST3GAL4 Q11206 ST3 beta-galactoside alpha-2,3-sialyltransferase 4 4.0E-02 0.588 0.692
SORT1 Q99523 sortilin 1 Transporter 1.00 0.573 0.615
SERPINC1 P01008 serpin family C member 1 Enzyme modulator 1.00 0.507 0.769
SERPINB2 P05120 serpin family B member 2 Enzyme modulator 6.4E-12 0.502 0.808
PTGS1 P23219 prostaglandin-endoperoxide synthase 1 Enzyme 6.2E-07 0.460 0.885
PPARGC1B Q86YN6 PPARG coactivator 1 beta Transcription factor 0.50 0.569 0.731
PPARG P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 2.9E-02 0.358 0.885
PPARA Q07869 peroxisome proliferator activated receptor alpha Nuclear receptor 3.0E-02 0.432 0.885
PCSK9 Q8NBP7 proprotein convertase subtilisin/kexin type 9 Enzyme 2.7E-17 0.482 0.808
PCSK7 Q16549 proprotein convertase subtilisin/kexin type 7 4.2E-03 0.631 0.615
NR1I2 O75469 nuclear receptor subfamily 1 group I member 2 Nuclear receptor 7.3E-09 0.418 0.846
NPC1L1 Q9UHC9 NPC1 like intracellular cholesterol transporter 1 Transporter 2.3E-20 0.656 0.423
NAMPT P43490 nicotinamide phosphoribosyltransferase Signaling 0.98 0.502 0.808
MMP14 P50281 matrix metallopeptidase 14 Enzyme 1.00 0.447 0.769
LRP8 Q14114 LDL receptor related protein 8 1.00 0.644 0.346
LRP1 Q07954 LDL receptor related protein 1 1.00 0.482 0.769
LPA P08519 lipoprotein(a) Enzyme 6.6E-89 0.444 0.769
LIPC P11150 lipase C, hepatic type Enzyme 3.3E-07 0.585 0.654
LEPR P48357 leptin receptor Signaling 0.99 0.433 0.808
LDLR P01130 low density lipoprotein receptor 9.8E-24 0.449 0.885
LCAT P04180 lecithin-cholesterol acyltransferase Enzyme 8.1E-02 0.588 0.654
KL Q9UEF7 klotho Enzyme 2.2E-04 0.448 0.769